Mouse anti-CD7, Clone: T3-3A1, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2448030.1MG
Ensure accurate, reproducible results in Flow Cytometry, ImmunofluorescenceCD7 Monoclonal antibody specifically detects CD7 in Human samples. It is validated for Flow Cytometry, Immunofluorescence.
|10mM PBS and 0.05% BSA with 0.05% Sodium Azide|
|CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein|
|Protein A or G purified|
|Store at 4C.|
|Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.|
|Flow Cytometry, Immunofluorescence|
|Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml|
|Human T cells|
|Cytokine Research, Signal Transduction|
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For Research Use Only