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  6. Mouse anti-Chorionic Gonadotropin beta Chain(HCG beta), Clone: HCGb/211, Novus Biologicals™

Mouse anti-Chorionic Gonadotropin beta Chain(HCG beta), Clone: HCGb/211, Novus Biologicals™
SDP

Catalog No. NBP24512802 Shop All R&D Systems Products
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NBP24512802 0.2 mg
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Catalog No. NBP24512802 Supplier Novus Biologicals Supplier No. NBP2451280.2MG

Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Immunohistochemistry (Frozen)

Chorionic Gonadotropin beta Chain (hCG beta) Monoclonal antibody specifically detects Chorionic Gonadotropin beta Chain (hCG beta) in Human samples. It is validated for Immunohistochemistry-Frozen, SDS-Page.

Specifications

Antigen Chorionic Gonadotropin beta Chain (HCG beta)
Applications Immunohistochemistry (Frozen), SDS-Page
Classification Monoclonal
Clone HCGb/211
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml, SDS-Page
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. P01233
Gene Alias CGB3choriogonadotropin subunit beta, CGB5, CGB7, CGB8, CG-beta, Chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit, chorionic gonadotropin, beta polypeptide, hCGB
Gene Symbols CGB
Host Species Mouse
Immunogen Purified human HCG-beta
Molecular Weight of Antigen 22 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Cancer
Primary or Secondary Primary
Gene ID (Entrez) 1082
Test Specificity This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1
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