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  6. Mouse anti-Fc gamma RIIIA/CD16a, Clone: C16/1045, Novus Biologicals™

Mouse anti-Fc gamma RIIIA/CD16a, Clone: C16/1045, Novus Biologicals™
SDP

Catalog No. NBP24483502 Shop All R&D Systems Products
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0.2 mg
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NBP24483502 0.2 mg
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Catalog No. NBP24483502 Supplier Novus Biologicals Supplier No. NBP2448350.2MG

Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

Fc gamma RIIIA/CD16a Monoclonal antibody specifically detects Fc gamma RIIIA/CD16a in Human samples. It is validated for Flow Cytometry, SDS-Page, Immunofluorescence.

Specifications

Antigen Fc gamma RIIIA/CD16a
Applications Flow Cytometry, SDS-Page, Immunofluorescence
Classification Monoclonal
Clone C16/1045
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. P08637, P08637
Gene Alias CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA
Gene Symbols FCGR3A
Host Species Mouse
Immunogen Recombinant human CD16 protein
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 2214
Test Specificity It recognizes CD16 (Fcgamma RIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80kDa. Two similar genes represent CD16, CD16A (Fcgamma RIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fcgamma RIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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