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  6. Mouse anti-Fibronectin/Anastellin, Clone: TV-1, Azide Free, Novus Biologicals™

Mouse anti-Fibronectin/Anastellin, Clone: TV-1, Azide Free, Novus Biologicals™
SDP

Catalog No. NBP23450402 Shop All R&D Systems Products
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0.2 mg
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NBP23450402 0.2 mg
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Catalog No. NBP23450402 Supplier Novus Biologicals Supplier No. NBP2345040.2 MG

Description

Mouse Monoclonal Antibody

Fibronectin Monoclonal antibody specifically detects Fibronectin in Human, Mouse, Rat, Porcine samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.

Specifications

Antigen Fibronectin
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone TV-1
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, CyTOF-ready
Formulation 10mM PBS - BSA free with No Preservative
Gene Accession No. P02751
Gene Symbols FN1
Host Species Mouse
Immunogen T-cell lymphoma biopsy
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Cancer, Cellular Markers, Extracellular Matrix, Mesenchymal Stem Cell Markers, Neuronal Stem Cell Markers, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 2335
Test Specificity Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.
Reconstitution Protein A purified
Target Species Human, Mouse, Rat, Pig
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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