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Mouse anti-hCG Beta, Clone: HCGb/54, Azide Free, Novus Biologicals™

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2331100.2MG

Catalog No. NBP23311002

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Specifications

Specifications

Chorionic Gonadotropin beta Chain (HCG beta)
HCGb/54
Unconjugated
10mM PBS - BSA free with No Preservative
CGB3choriogonadotropin subunit beta, CGB5, CGB7, CGB8, CG-beta, Chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit, chorionic gonadotropin, beta polypeptide, hCGB
Mouse
IgG1 Kappa
Protein A or G purified
RUO
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Monoclonal
This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Human
Western Blot, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
1.0 mg/mL
Western Blot 0.5-1ug/ml, ELISA 1-5ug/ml for coating, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Purified
CGB
Chorionic Gonadotropin beta Antibody (HCGb/54)
22 kDa
0.2 mg
Cancer
Primary
1082
Protein A purified
Documents
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