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HLA-DR Mouse anti-Human, APC-R700, Clone: G46-6, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 565128

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Catalog No. BDB565128


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Description

Description

The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

Specifications

Specifications

HLA-DR
G46-6
MHC class II antigen; HLA class II histocompatibility antigen
Affinity Purified
IgG2a, κ
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
APC-R700
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Murine
Affinity Chromatography
RUO
Primary
Human
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