Mouse anti-Human CD59/MACIF/MIRL/Protectin Monoclonal Antibody, Clone: BRA-10G, Epredia™ LabVision

Mouse Monoclonal Antibody

Supplier:  Epredia MS507P0

Catalog No. MS507P0

Description

CD59 (also known as membrane attack complex inhibition factor (MACIF), membrane inhibitor of reactive lysis (MIRL), homologous restriction factor (HRF20), and Protectin) is a glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 is widely distributed on cells in all tissues. It inhibits formation of MAC, thus protecting cells from complement mediated lysis. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobulinuria (PNH).

Host Species: Mouse
Clone: BRA-10G
Isotype: IgG1/κ
Cross Reactivity: Human, Others not-known
Epitope: Not determined
Immunogen: Human K562 tumor cells
Molecular Weight: 20kDa
Positive Control: Daudi, CEM, K562, Jurkat, Raji, and human lymphocytes. Lymph node or tonsil.
Cellular Localization: Cell membrane

Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Specifications

• Antigen: CD59/MACIF/MIRL/Protectin Ab-2
• Concentration: 200μg/mL
• Immunogen: Human K562 tumor cells
• Primary or Secondary: Primary
• Form: Purified

• Classification: Monoclonal
• Host Species: Mouse
• Quantity: 100 μL
• Target Species: Human
• Isotype: IgG1 κ