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Mouse anti-Human CD59/MACIF/MIRL/Protectin Monoclonal Antibody, Clone: BRA-10G, Epredia™ LabVision
Mouse Monoclonal Antibody
Specifications
| Antigen | CD59/MACIF/MIRL/Protectin Ab-2 |
|---|---|
| Classification | Monoclonal |
| Form | Purified |
| Host Species | Mouse |
| Target Species | Human |
| Catalog Number | Mfr. No. | Concentration | Quantity | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Concentration | Quantity | Price | Quantity & Availability | ||||
|
MS507P0
|
Epredia
MS507P0 |
200μg/mL | 100 μL | N/A | N/A | N/A | |||
|
MS507P1ABX
|
Epredia
MS507P1ABX |
1mg/mL | 100 μL | N/A | N/A | N/A | |||
|
MS507PABX
|
Epredia
MS507PABX |
1mg/mL | 200 μL | N/A | N/A | N/A | |||
Description
CD59 (also known as membrane attack complex inhibition factor (MACIF), membrane inhibitor of reactive lysis (MIRL), homologous restriction factor (HRF20), and Protectin) is a glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 is widely distributed on cells in all tissues. It inhibits formation of MAC, thus protecting cells from complement mediated lysis. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobulinuria (PNH).
Host Species: Mouse
Clone: BRA-10G
Isotype: IgG1/κ
Cross Reactivity: Human, Others not-known
Epitope: Not determined
Immunogen: Human K562 tumor cells
Molecular Weight: 20kDa
Positive Control: Daudi, CEM, K562, Jurkat, Raji, and human lymphocytes. Lymph node or tonsil.
Cellular Localization: Cell membrane
Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly
Specifications
| CD59/MACIF/MIRL/Protectin Ab-2 | |
| Purified | |
| Human | |
| IgG1 κ |
| Monoclonal | |
| Mouse | |
| Human K562 tumor cells | |
| Primary |
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