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  6. Mouse anti-Melan-A/MART-1, Clone: M2-7C10 + M2-9E3, Azide Free, Novus Biologicals™

Mouse anti-Melan-A/MART-1, Clone: M2-7C10 + M2-9E3, Azide Free, Novus Biologicals™
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Catalog No. NBP23468002 Shop All R&D Systems Products
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NBP23468002 0.2 mg
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Catalog No. NBP23468002 Supplier Novus Biologicals Supplier No. NBP2346800.2 MG

Description

Mouse Monoclonal Antibody

Melan-A/MART-1 Monoclonal antibody specifically detects Melan-A/MART-1 in Human, Mouse, Rat samples. It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.

Specifications

Antigen Melan-A/MART-1
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone M2-7C10 + M2-9E3
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, CyTOF-ready
Formulation 10mM PBS - BSA free with No Preservative
Gene Accession No. Q16655
Gene Alias Antigen LB39-AA, Antigen SK29-AA, Mart 1 Melan A, MART1MART-1, melan-A, melanoma antigen recognized by T-cells 1, Protein Melan-A
Gene Symbols MLANA
Host Species Mouse
Immunogen Recombinant hMART-1 protein (M2-7C10; M2-9E3)
Molecular Weight of Antigen 21 kDa
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Cytoskeleton Markers, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 2315
Test Specificity This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Reconstitution Protein A purified
Target Species Human, Mouse, Rat
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG
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