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  6. Mouse anti-Melanoma Marker (MART-1 + Tyrosinase + gp100), Clone: A103 + T311 + HMB45, Novus Biologicals™

Mouse anti-Melanoma Marker (MART-1 + Tyrosinase + gp100), Clone: A103 + T311 + HMB45, Novus Biologicals™
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Catalog No. NBP23454702 Shop All R&D Systems Products
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0.2 mg
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NBP23454702 0.2 mg
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Catalog No. NBP23454702 Supplier Novus Biologicals Supplier No. NBP2345470.2 MG

Description

Mouse Monoclonal Antibody

Melanoma Marker (MART-1 + Tyrosinase + gp100) Monoclonal antibody specifically detects Melanoma Marker (MART-1 + Tyrosinase + gp100) in Human samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

Antigen Melanoma Marker (MART-1 + Tyrosinase + gp100)
Applications Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone A103 + T311 + HMB45
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Formulation 10mM PBS - BSA free with No Preservative
Gene Accession No. Q16655
Host Species Mouse
Immunogen Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2315
Test Specificity This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Reconstitution Protein A purified
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1, IgG2a κ
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