Mouse anti-Melanoma Marker (MART-1 + Tyrosinase + gp100), Clone: A103 + T311 + HMB45, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2345470.2 MG

Catalog No. NBP23454702

Description

Melanoma Marker (MART-1 + Tyrosinase + gp100) Monoclonal antibody specifically detects Melanoma Marker (MART-1 + Tyrosinase + gp100) in Human samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

• Antigen: Melanoma Marker (MART-1 + Tyrosinase + gp100)
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
• Gene Accession No.: Q16655
• Immunogen: Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
• Quantity: 0.2 mg
• Primary or Secondary: Primary
• Test Specificity: This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
• Target Species: Human
• Form: Purified

• Applications: Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: A103 + T311 + HMB45
• Conjugate: Unconjugated
• Formulation: 10mM PBS - BSA free with No Preservative
• Host Species: Mouse
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Gene ID (Entrez): 2315
• Reconstitution: Protein A purified
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG1, IgG2a κ

For Research Use Only