Mouse anti-Myeloid Cell Marker, Clone: BM-1, Azide Free, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2345620.2 MG

Catalog No. NBP23456202

Description

Myeloid Cell Marker Monoclonal antibody specifically detects Myeloid Cell Marker in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.

Specifications

• Antigen: Myeloid Cell Marker
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, CyTOF-ready
• Host Species: Mouse
• Molecular Weight of Antigen: 183 kDa
• Quantity: 0.2 mg
• Primary or Secondary: Primary
• Reconstitution: Protein A purified
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG1

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: BM-1
• Conjugate: Unconjugated
• Formulation: 10mM PBS - BSA free with No Preservative
• Immunogen: Human peripheral blood mononuclear cells
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Test Specificity: Recognizes 183kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This MAb reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.
• Target Species: Human
• Form: Purified

For Research Use Only