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Mouse anti-Renal Cell Carcinoma (gp200), Clone: 66.4.C2 (PN-15), Azide Free, Novus Biologicals™
SDP

Catalog No. NBP23315202 Shop All R&D Systems Products
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0.2 mg
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NBP23315202 0.2 mg
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Catalog No. NBP23315202 Supplier Novus Biologicals Supplier No. NBP2331520.2MG

Specifications

Antigen Renal Cell Carcinoma (gp200)
Applications ELISA
Classification Monoclonal
Clone 66.4.C2 (PN-15)
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution ELISA 1-5ug/ml for coating
Formulation 10mM PBS - BSA free with No Preservative
Gene Alias CD205LY-75, CLEC13BLy-75, C-type lectin domain family 13 member B, DEC-205CD205 antigen, GP200-MR6, lymphocyte antigen 75
Gene Symbols LY75
Host Species Mouse
Immunogen Fresh, normal human renal cortical tissue homogenate was used as immunogen to generate the RCC antibody.
Purification Method Protein G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Dendritic Cell Markers, Ovarian Carcinoma Cell Markers, Renal Cell Carcinoma Cell Markers, Vision
Primary or Secondary Primary
Gene ID (Entrez) 4065
Test Specificity Recognizes a glycoprotein of ∼200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
Target Species Human, Equine
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG2b κ
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