SMARCA4, Mouse, Clone: BRG-01, Abnova™

Mouse monoclonal antibody raised against partial recombinant SMARCA4.

Supplier:  Abnova Corporation MAB6460

Catalog No. 89-112-878

Description

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: SMARCA4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (10 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: SMARCA4
• Gene Symbols: SMARCA4
• Immunogen: Recombinant GST fusion protein corresponding to C-terminus 242 amino acids of human SMARCA4.
• Regulatory Status: RUO
• Gene ID (Entrez): 6597
• Content And Storage: Store at 4°C. Do not freeze.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG2a

• Applications: Western Blot
• Clone: BRG-01
• Description: Mouse monoclonal antibody raised against partial recombinant SMARCA4.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene Alias: BAF190/BRG1/FLJ39786/SNF2/SNF2-BETA/SNF2L4/SNF2LB/SWI2/hSNF2b
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid