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Mouse anti-TLR2, Clone: TLR2/221, Novus Biologicals™

Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2451640.02MG
Description
Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
TLR2 Monoclonal specifically detects TLR2 in Human, Canine, Monkey samples. It is validated for Functional.Specifications
TLR2 | |
Monoclonal | |
0.2 mg/mL | |
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml | |
O60603 | |
TLR2 | |
Recombinant human TLR2 protein | |
Protein A or G purified | |
RUO | |
Primary | |
This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. | |
Store at 4C. | |
IgG2a κ |
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence | |
TLR2/221 | |
Unconjugated | |
10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
CD282 antigen, TIL4CD282, toll/interleukin 1 receptor-like 4, Toll/interleukin-1 receptor-like protein 4, toll-like receptor 2 | |
Mouse | |
90 kDa | |
0.02 mg | |
Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Toll Like Receptors | |
7097 | |
Human, Canine, Monkey | |
Purified |
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