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Mouse anti-TLR4, Clone: TLR4/230, Novus Biologicals™

Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2451700.1MG
Description
Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
TLR4 Monoclonal specifically detects TLR4 in Human, Rat, Porcine, Canine, Guinea Pig, Monkey samples. It is validated for Functional.Specifications
TLR4 | |
Monoclonal | |
0.2 mg/mL | |
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml | |
O00206 | |
TLR4 | |
Recombinant human TLR4 protein | |
0.1 mg | |
Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Toll Like Receptors | |
7099 | |
Human, Rat, Pig, Canine, Guinea Pig, Monkey | |
Purified |
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence | |
TLR4/230 | |
Unconjugated | |
10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
ARMD10, CD284, CD284 antigen, hTollhomolog of Drosophila toll, TOLL, toll-like receptor 4 | |
Mouse | |
Protein A or G purified | |
RUO | |
Primary | |
This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. | |
Store at 4C. | |
IgG2a κ |
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