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Mouse anti-TLR4, Clone: TLR4/230, Novus Biologicals™
SDP

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2451700.1MG

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Catalog No. NBP24517001


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Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

TLR4 Monoclonal specifically detects TLR4 in Human, Rat, Porcine, Canine, Guinea Pig, Monkey samples. It is validated for Functional.
Specifications

Specifications

TLR4
Monoclonal
0.2 mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
O00206
TLR4
Recombinant human TLR4 protein
0.1 mg
Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Toll Like Receptors
7099
Human, Rat, Pig, Canine, Guinea Pig, Monkey
Purified
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
TLR4/230
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
ARMD10, CD284, CD284 antigen, hTollhomolog of Drosophila toll, TOLL, toll-like receptor 4
Mouse
Protein A or G purified
RUO
Primary
This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Store at 4C.
IgG2a κ
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