Invitrogen™ MRPL28 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103523

Catalog No. PIPA5103523

Description

Antibody detects endogenous levels of total MRPL28.

MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein that belongs to the ribosomal protein L28P family. MRP-L28 potentially represents an important therapeutic reagent for HLA-A24 (A24) patients as this antigen is recognized by tumor-infiltrating lymphocyte (TIL) 1290, which targets the A24 serotype. HLAA24 (A24) is an HLA-A serotype that identifies the more common HLA-A24 gene products. A24 is a split antigen that is also recognized by the A9 broad antigen type and the similar A23 types. A24 is common in Austronesia and has one of the highest A allele frequencies for a number of peoples, including Papua New Guineans, indigeonous Taiwanese (eastern tribals), Yupik and Greenland Eskimos. MRP-L28 is found in a variety of normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung and retinal tissue.

Specifications

• Antigen: MRPL28
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL28
• Gene Alias: 1110015G04Rik; 39S ribosomal protein L28, mitochondrial; HGNC6756; L28mt; MAAT 1; MAAT1; Melanoma antigen p15; melanoma-associated antigen recognised by cytotoxic T lymphocytes; melanoma-associated antigen recognized by T lymphocytes; melanoma-associated antigen recognized by T-lymphocytes; MGC8499; Mitochondrial large ribosomal subunit protein bL28m; mitochondrial ribosomal protein L28; MRP L28; MRPL 28; MRPL28; MRP-L28; p15
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10573, 68611
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q13084, Q9D1B9
• Gene Symbols: MRPL28
• Immunogen: A synthesized peptide derived from human MRPL28(Accession Q13084), corresponding to amino acid residues L146-I196.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Monkey
• Product Type: Antibody
• Isotype: IgG