MSRA Monoclonal Antibody (C6), Invitrogen™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
FEMA550974	Invitrogen™ MA550974	20 μL
FEMA550973	Invitrogen™ MA550973	200 μL

Description

Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.

Specifications

• Antigen: MSRA
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Alias: 2310045J23Rik; 6530413P12Rik; cytosolic methionine-S-sulfoxide reductase; methionine sulfoxide reductase A; mitochondrial peptide methionine sulfoxide reductase; Msra; MSR-A; peptide met (O) reductase; peptide Met(O) reductase; peptide methionine sulfoxide reductase; peptide-methionine (S)-S-oxide reductase; PMSR; protein-methionine-S-oxide reductase
• Gene Symbols: Msra
• Isotype: IgG1 κ
• Purification Method: Protein A/G
• Gene: Msra

• Clone: C6
• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Rat, Pig
• Gene Accession No.: Q923M1, Q9UJ68
• Gene ID (Entrez): 100152960, 29447, 4482
• Immunogen: Recombinant Human MSRA protein, Ala27-Lys235 (Accession #Q9UJ68).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.