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  6. Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent

Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent

Catalog No. 03170450
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Standard Components:
MSTFA
MSTFA + 1% TMCS
MTBSTFA
Quantity:
10 g
10 x 1 mL ampules
100 mL
25 mL
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Catalog No. Standard Components Quantity
03-170-450 MTBSTFA 100 mL
PI48911 MSTFA 10 g
PI48910 MSTFA 10 x 1 mL ampules
PI48915 MSTFA + 1% TMCS 10 x 1 mL ampules
PI48913 MSTFA 25 mL
PI48914 MSTFA 100 mL
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Catalog No. 03-170-450 Supplier Thermo Scientific™ Supplier No. TS48929

Description

Offer maximum volatility with the Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent.

Use Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent for GC analyses of early eluting compounds that would otherwise be obscured in the chromatogram. MSTFA, the most volatile TMS-amide available, and its byproduct N-methyltrifluoroacetamide typically elute with the solvent front, allowing TMS derivatives of small molecules to be analyzed. Addition of Thermo Scientific™ TMCS aids derivatization of amides, secondary amines, and hindered hydroxyls not derivatized by MSTFA alone.

  • Trimethylsilyl donor strength comparable to BSA and BSTFA
  • Reacts to replace labile hydrogens on a wide range of polar compounds with a Si(CH3)3 group
  • Used to prepare volatile and thermally stable derivatives for GC and MS
  • Volatile byproduct, N-methyltrifluoroacetamide, has an even lower retention time than MSTFA
  • Often TMS derivatives of small molecules can be analyzed when derivatized with MSTFA because the byproducts and the reagent itself usually elute with the solvent front
  • Addition of Thermo Scientfic TMCS aids derivatization of amides, secondary amines and hindered hydroxyls not derivatized by MSTFA alone
    • TRUSTED_SUSTAINABILITY

    Specifications

    For Use With GC/MS
    Standard Concentration 98 to 100%
    Hazards Flammable, Irritant
    Quantity 100 mL
    Standard Components MTBSTFA

    For Research Use Only. Not for use in diagnostic procedures.

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