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MTA2 Mouse anti-Human, Mouse, Clone: 2G12G4, Proteintech
SDP

Mouse Monoclonal Antibody

$518.60

Specifications

Antigen MTA2
Clone 2G12G4
Concentration 1.4 mg/mL
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-6629
SDP
Encompass_Preferred
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Proteintech Group Inc
661951IG150UL
150 μL
Each of 1 for $518.60
Only null left
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Description

Description

This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
Specifications

Specifications

MTA2
1.4 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Metastasis associated 1 like 1, MTA1 L1 protein, MTA1L1, MTA2, PID
MTA2
IgG2b
Protein A
Antibody
2G12G4
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Mouse
Human, Mouse
O94776, Q9R190
23942, 9219
MTA2 Fusion Protein Ag11713
Primary
-20°C
MTA2
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SDS
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Documents

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