MUC2 Antibody (MLP/842) - IHC-Prediluted, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP248391

Catalog No. NBP248391

Description

MUC2 Monoclonal specifically detects MUC2 in Human, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: MUC2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: MUC2
• Immunogen: Recombinant fragment covering tandem repeats of human MUC2 protein (exact sequence is proprietary) (Uniprot: Q02817 )
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This monoclonal antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium.MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin)
• Clone: MLP/842
• Dilution: Immunohistochemistry-Paraffin
• Gene Alias: Intestinal mucin-2, MLP, MUC-2, mucin 2, intestinal/tracheal, mucin 2, oligomeric mucus/gel-forming, mucin-2, mucin-like protein, SMUC
• Host Species: Mouse
• Molecular Weight of Antigen: 520 kDa
• Quantity: 7 mL
• Research Discipline: Cancer, Cellular Markers, Inflammation, Signal Transduction
• Gene ID (Entrez): 4583
• Target Species: Human, Rat (Negative)
• Form: Purified