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  6. MUC5AC Antibody (45M1) - Azide and BSA Free, Novus Biologicals™

MUC5AC Antibody (45M1) - Azide and BSA Free, Novus Biologicals™
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Catalog No. NBP23273202 Shop All R&D Systems Products
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NBP23273202 0.2 mg
NBP23273201 0.1 mg
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Catalog No. NBP23273202 Supplier Novus Biologicals Supplier No. NBP2327320.2MG

Description

Mouse Monoclonal Antibody

MUC5AC Monoclonal antibody specifically detects MUC5AC in Human, Mouse, Rat, Porcine, Chicken, Feline, Primate, Rabbit, Bovine (Negative) samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.

Specifications

Antigen Mucin 5AC
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 45M1
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1.0ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5ug/ml, CyTOF-ready
Formulation 10mM PBS - BSA free with No Preservative
Gene Accession No. P98088
Gene Alias gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin
Gene Symbols MUC5AC
Host Species Mouse
Immunogen M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
Purification Method Protein G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Extracellular Matrix
Primary or Secondary Primary
Gene ID (Entrez) 4586
Test Specificity This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
Target Species Human, Mouse, Rat, Pig, Chicken, Feline, Primate, Rabbit, Bovine (Negative)
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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