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MUC6 Antibody (MUC6/916), Alexa Fluor™ 532, Novus Biologicals™
SDP

Catalog No. NP247799A32 Shop All R&D Systems Products
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NP247799A32 0.1 mL
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Catalog No. NP247799A32 Supplier Novus Biologicals Supplier No. NBP247799AF532
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Description

Mouse Monoclonal Antibody

MUC6 Monoclonal specifically detects MUC6 in Human, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen MUC6
Applications Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone MUC6/916
Conjugate Alexa Fluor 532
Dilution Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias gastric mucin, Gastric mucin-6, MUC-6, mucin 6, gastric, mucin 6, oligomeric mucus/gel-forming, mucin-6
Gene Symbols MUC6
Host Species Mouse
Immunogen Recombinant fragment covering tandem repeats of human MUC6 protein (exact sequence is proprietary) (Uniprot: Q6W4X9)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 4588
Test Specificity The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
Target Species Human, Rat
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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