Invitrogen™ Myeloperoxidase Recombinant Rabbit Monoclonal Antibody (RM407)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA536073

Catalog No. PIMA536073

Description

This antibody may also react to mouse or rat MPO, as predicted by immunogen homology.

Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.

Specifications

• Antigen: Myeloperoxidase
• Classification: Recombinant Monoclonal
• Concentration: 0.01 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
• Gene Accession No.: P05164
• Gene Symbols: MPO
• Immunogen: A peptide corresponding to the internal region of light chain on MPO (aa 150-250).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: RM407
• Conjugate: Unconjugated
• Gene: MPO
• Gene Alias: 84 kDa myeloperoxidase; 89 kDa myeloperoxidase; mKIAA4033; MPO; Myeloperoxidase; Myeloperoxidase heavy chain; Myeloperoxidase light chain
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4353
• Content And Storage: -20°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov