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NAG-1 Monoclonal Antibody (6D12.H10.E4), Rockland™

Rat Monoclonal Antibody
Supplier: Rockland Immunochemicals 200501B07

Description
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody reacts with the C-terminus of endogenous NAG-1 protein from mouse tissues. A BLAST analysis suggests reactivity with NAG-1 from chimpanzee and macaque based on a 100% homology. Partial reactivity is expected against rat based on an 86% homology with the immunizing sequence. Cross-reactivity with NAG-1 from other sources has not been determined.
Bone morphogenetic proteins (e. g., BMP5, MIM 112265) are members of the transforming growth factor-beta (see TGFB1, MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.Specifications
NAG-1 | |
Monoclonal | |
1.09 mg/mL | |
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2 | |
Q99988, Q9Z0J7 | |
Gdf15 | |
This Protein-A purified antibody was prepared by repeated immunizations with an MBP-tagged recombinant protein produced in E.coli corresponding to C-term mouse NAG-1 protein. Cross reactivity to MBP is negative. | |
RUO | |
23886, 9518 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunoprecipitation, Western Blot | |
6D12.H10.E4 | |
Unconjugated | |
Gdf15 | |
GDF15; GDF-15; growth differentiation factor 15; Growth/differentiation factor 15; macrophage inhibiting cytokine-1; Macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; Placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; Sbf | |
Rat | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody | |
IgG2a λ |
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