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Nateglinide, Tocris Bioscience™
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Catalog No. 423150
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Kir6 (KATP) blocker; displays high affinity for SUR1/Kir6.2 channels

Kir6 (KATP) blocker. Exhibits in vitro tissue selectivity for pancreatic β-cell-type Kir6 channels over cardiovascular Kir6 channels; displays high affinity for SUR1/Kir6.2 channels. Hypoglycemic agent; stimulates insulin secretion from pancreatic β-cells by increasing cytosolic Ca2+ concentration. Also agonist at the orphan receptor MRGPRX4.

Chemical Identifiers

CAS 105816-04-4
Molecular Formula C19H27NO3
Molecular Weight (g/mol) 317.429
InChI Key OELFLUMRDSZNSF-OFLPRAFFSA-N
Synonym nateglinide, starlix, fastic, starsis, senaglinide, trazec, sdz-djn-608, nateglinide inn, unii-41x3pwk4o2, chembl783
PubChem CID 5311309
IUPAC Name (2R)-3-phenyl-2-[(4-propan-2-ylcyclohexanecarbonyl)amino]propanoic acid
SMILES CC(C)C1CCC(CC1)C(=O)NC(CC2=CC=CC=C2)C(=O)O

Specifications

Quantity 50 mg
Formula Weight 317.42
Percent Purity >98%
Chemical Name or Material Nateglinide

Safety and Handling

Recommended Storage Store at Room Temperature
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