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R&D Systems™ NBI 35965 hydrochloride
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Catalog No. 310050 Shop All Novus Products
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Catalog No. Quantity
31-005-0 50 mg
31-001-0 10 mg
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Catalog No. 31-005-0 Supplier R&D Systems™ Supplier No. 3100/50

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Description

A Tocris product, part of R&D Systems. Potent and selective CRF1 antagonist

Potent and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist (Ki values are 4 and > 10000 nM at CRF1 and CRF2 respectively). Inhibits cAMP accumulation and adrenocorticotropic hormone (ACTH) production in vitro (pIC50 values are 7.1 and 6.9 respectively) and attenuates CRF and ACTH production in vivo. Orally active and brain penetrant with anxiolytic activity.

Chemical Identifiers

CAS 603151-83-3
Molecular Formula C21H23Cl3N4

Specifications

Quantity 50 mg
Product Line Tocris
Formula Weight 437.79
Purity >98%
Molecular Weight (g/mol) 437.793
Chemical Name or Material NBI 35965 hydrochloride

Safety and Handling

Recommended Storage Store at Room Temperature
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