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(±)-NBI 74330, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
This item is not returnable. View return policy
473722-68-8
C32H27F4N5O3
605.594
XMRGQUDUVGRCBS-UHFFFAOYSA-N
n-1-3-4-ethoxyphenyl-4-oxopyrido 2,3-d pyrimidin-2-yl ethyl-2-4-fluoro-3-trifluoromethyl phenyl-n-pyridin-3-ylmethyl acetamide,d0a8pv,plusmn-nbi 74330,gtpl839,n-1-3-4-ethoxyphenyl-3,4-dihydro-4-oxopyrido 2,3-d pyrimidin-2-yl ethyl-4-fluoro-n-3-pyridinylmethyl-3-trifluoromethyl benzeneacetamide
10167713
N-[1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide
CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC(=C(C=C5)F)C(F)(F)F
This item is not returnable. View return policy
473722-68-8
C32H27F4N5O3
605.594
XMRGQUDUVGRCBS-UHFFFAOYSA-N
n-1-3-4-ethoxyphenyl-4-oxopyrido 2,3-d pyrimidin-2-yl ethyl-2-4-fluoro-3-trifluoromethyl phenyl-n-pyridin-3-ylmethyl acetamide,d0a8pv,plusmn-nbi 74330,gtpl839,n-1-3-4-ethoxyphenyl-3,4-dihydro-4-oxopyrido 2,3-d pyrimidin-2-yl ethyl-4-fluoro-n-3-pyridinylmethyl-3-trifluoromethyl benzeneacetamide
10167713
N-[1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide
CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC(=C(C=C5)F)C(F)(F)F

Potent and selective CXCR3 antagonist

Potent and selective CXCR3 antagonist; potently inhibits 125I-CXCL10 binding to CXCR3 (pKi = 8.13). Inhibits calcium mobilization in response to CXCL11 and CXCL10 in RBL cells. Exhibits no significant effect on chemotaxis induced by CXCR4 or CCR7. Displays a five-fold greater affinity for CXCR3 than (±)-AMG 487 .

This product is racemic.

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Quantity 10mg
Formula Weight 605.58
Chemical Name or Material (±)-NBI 74330

Recommended Storage : Store at -20°C