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Tocris Bioscience™ (±)-NBI 74330
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Catalog No. 452810
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10 mg
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Catalog No. Quantity
45-281-0 10 mg
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Catalog No. 45-281-0 Supplier Tocris Bioscience™ Supplier No. 4528/10
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Description

Potent and selective CXCR3 antagonist

Potent and selective CXCR3 antagonist; potently inhibits 125I-CXCL10 binding to CXCR3 (pKi = 8.13). Inhibits calcium mobilization in response to CXCL11 and CXCL10 in RBL cells. Exhibits no significant effect on chemotaxis induced by CXCR4 or CCR7. Displays a five-fold greater affinity for CXCR3 than (±)-AMG 487 .

This product is racemic.

Chemical Identifiers

CAS 473722-68-8
Molecular Formula C32H27F4N5O3

Specifications

Quantity 10 mg
Formula Weight 605.58
Molecular Weight (g/mol) 605.594
Chemical Name or Material (±)-NBI 74330

Safety and Handling

Recommended Storage Store at -20°C
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