Tocris Bioscience™ NBQX disodium salt

Description

Potent AMPA antagonist; more water soluble form of NBQX (Cat. No. 0373)

NBQX disodium salt is a selective and competitive AMPA and kainate receptor antagonist (IC50 = 0.15 μM and 4.8 μM, respectively). NBQX blocks the antidepressant effects of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529), decreases mTOR and BDNF levels. NBQX is neuroprotective, anticonvulsant, antinociceptive and active in vivo.

NBQX disodium salt is a more water-soluble form of NBQX (Cat. No. 0373).

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Specifications

• Chemical Name or Material: 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt
• CAS: 479347-86-9
• Assay Percent Range: >98%
• Quantity: 10 mg
• Solubility: Soluble to 100mM in water
• Molecular Formula: C₁₂H₆N₄O₆SNa₂
• Formula Weight: Observed MW: 380.24

For Research Use Only