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Tocris Bioscience™ NDT 9513727



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Quantity:
10 mg
50 mg
Description
Potent C5a receptor (C5aR) negative allosteric modulator (NAM) (IC50 = 11.6 nM); selective for human C5aR (IC50 values for rat and mouse C5aR are > 10 μM). Exhibits inverse agonist pharmacokinetics. Blocks degranulation response in C5a-stimulated U937 cells (IC50 = 7.1 nM). Exhibits selectivity for primate and gerbil receptor over other species. Orally bioavailable.
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Specifications
Specifications
Quantity | 50 mg |
Formula Weight | 573.68 |
Purity | >98% |
Molecular Weight (g/mol) | 573.693 |
Chemical Name or Material | NDT 9513727 |
Safety and Handling
Recommended Storage | Store at +4°C |
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