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Neprilysin/CD10 Antibody (CB-CALLA), Novus Biologicals™
SDP

Catalog No. NBP24486900 Shop All R&D Systems Products
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NBP24486900 0.02 mg
NBP24486901 0.1 mg
NBP24486902 0.2 mg
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Catalog No. NBP24486900 Supplier Novus Biologicals Supplier No. NBP2448690.02MG
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

Neprilysin/CD10 Monoclonal specifically detects Neprilysin/CD10 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen Neprilysin/CD10
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone CB-CALLA
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. P08473
Gene Alias Atriopeptidase, CALLAmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase), CD10 antigen, CD10), CD10membrane metallo-endopeptidase variant 1, Common acute lymphocytic leukemia antigen, DKFZp686O16152, EC 3.4.24, EC 3.4.24.11, Enkephalinase, EPN, membrane metallo-endopeptidase, membrane metallo-endopeptidase variant 2, MGC126681, MGC126707, NEPmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, neprilysin, Neutral endopeptidase, Neutral endopeptidase 24.11, SFE, Skin fibroblast elastase
Gene Symbols MME
Host Species Mouse
Immunogen Human CD10
Molecular Weight of Antigen 100 kDa
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cytokine Research, Immunology, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 4311
Test Specificity Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG2b κ
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