Invitrogen™ Neurogranin Monoclonal Antibody (C2)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA541648	Invitrogen™ MA541648	200 μL
PIMA543647	Invitrogen™ MA543647	20 μL

Description

Neurogranin Monoclonal Antibody for Western Blot, IHC (P)

Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

Specifications

• Antigen: Neurogranin
• Concentration: 1 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q92686
• Gene ID (Entrez): 4900
• Immunogen: Recombinant protein Neurogranin. The antigen corresponds to amino acid range 1-67 of the target protein.
• Product Type: Antibody

• Clone: C2
• Content And Storage: -20°C
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG1 κ
• Target Species: Human
• Gene: NRGN
• Gene Alias: 0710001B06Rik; AI838505; B-50 immunoreactive C-kinase substrate; BICKS; calmodulin-binding protein; hng; NEUG(55-78); Neurogranin; neurogranin (protein kinase C substrate, RC3); ng; NG/RC3; NRGN; p17; postsynaptic spine 1; protein kinase C substrate; protein kinase C substrate 7.5 kDa protein; protein kinase C substrate, RC3; Pss1; R75334; RC3; similar to neurogranin
• Gene Symbols: NRGN
• Primary or Secondary: Primary
• Purification Method: Protein A/G