| Antigen |
NF-H |
| Applications |
Flow Cytometry, Immunohistochemistry (Paraffin) |
| Classification |
Monoclonal |
| Clone |
RT-97 + NR-4 |
| Conjugate |
Janelia Fluor 549 |
| Dilution |
Flow Cytometry, Immunohistochemistry-Paraffin |
| Formulation |
50mM Sodium Borate with 0.05% Sodium Azide |
| Gene Alias |
200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H |
| Gene Symbols |
NEFH |
| Host Species |
Mouse |
| Immunogen |
Triton-X 100 insoluble proteins of rat brain (RT-97); Neurofilaments from porcine spinal cord (NR-4) (Uniprot: P12036) |
| Purification Method |
Protein G purified |
| Quantity |
0.1 mL |
| Research Discipline |
Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience |
| Primary or Secondary |
Primary |
| Gene ID (Entrez) |
4744.0 |
| Test Specificity |
This monoclonal antibody reacts with a 200kDa and 68kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament. |
| Target Species |
Human, Mouse, Rat, Pig, Chicken |
| Content And Storage |
Store at 4°C in the dark. |
| Isotype |
IgG1 κ |
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