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NF-H Antibody (SPM203), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP247833A30 Shop All R&D Systems Products
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NP247833A30 0.1 mL
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Catalog No. NP247833A30 Supplier Novus Biologicals Supplier No. NBP247833AF350
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Description

Mouse Monoclonal Antibody

NF-H Monoclonal specifically detects NF-H in Human, Mouse, Rat, Porcine, Chicken samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen NF-H
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPM203
Conjugate Alexa Fluor 350
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias 200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H
Gene Symbols NEFH
Host Species Mouse
Immunogen Triton-X 100 insoluble protein fraction of rat brain (Uniprot: P12036)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 4744
Test Specificity This monoclonal antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Target Species Human, Mouse, Rat, Pig, Chicken
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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