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NF-L Antibody (NR-4) - IHC-Prediluted, Novus Biologicals™
SDP

Catalog No. NBP248292 Shop All R&D Systems Products
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NBP248292 7 mL
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Catalog No. NBP248292 Supplier Novus Biologicals Supplier No. NBP248292
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Description

Mouse Monoclonal Antibody

NF-L Monoclonal specifically detects NF-L in Human, Rat, Porcine, Bovine, Chicken samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen NF-L
Applications Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone NR-4
Conjugate Unconjugated
Dilution Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias 68 kDa neurofilament protein, neurofilament protein, light chain, neurofilament subunit NF-L, Neurofilament triplet L protein, neurofilament, light polypeptide, neurofilament-light, NF68FLJ53642, NF-L, NFLlight polypeptide 68kDa
Gene Symbols NEFL
Host Species Mouse
Immunogen Crude neurofilament preparation from porcine spinal cord
Molecular Weight of Antigen 68 kDa
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience
Primary or Secondary Primary
Gene ID (Entrez) 4747
Test Specificity This monoclonal antibody reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Target Species Human, Rat, Pig, Chicken, Primate
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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