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Invitrogen™ NFE4 Polyclonal Antibody
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Catalog No. PA549450
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400 μL
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PA549450 400 μL
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Catalog No. PA549450 Supplier Invitrogen™ Supplier No. PA549450
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Description

Rabbit Polyclonal Antibody

NFE4 Polyclonal Antibody for Western Blot

Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFE4
Applications Western Blot
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene NFE4
Gene Accession No. Q86UQ8
Gene Alias fetal globin activator NF-E4; gamma-globin gene activator; NFE4; NF-E4; nuclear factor, erythroid 4; transcription factor NF-E4
Gene Symbols NFE4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 135-169 amino acids from the C-terminal region of human NFE4.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58160
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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