NFE4 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA549450
DescriptionFunctions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
|KLH conjugated synthetic peptide between 135-169 amino acids from the C-terminal region of human NFE4.|
|Protein A, Antigen Affinity Chromatography|
|PBS with 0.09% sodium azide|
|Transcription factor NF-E4, NFE4|
|-20° C, Avoid Freeze/Thaw Cycles|
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