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NFPS, Tocris Bioscience™

Catalog No. 278910
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective non-transportable GlyT1 inhibitor

Selective, non-transportable inhibitor of GlyT1 which displays no activity at GABA or glutamate receptors (IC50 values are 2.8, 9.8 and 56000 nM for hGlyT1, rGlyT1 and rGlyT2 respectively). Enhances the amplitude of the NMDA component of glutamatergic EPSCs.

R-enantiomer also available.

Chemical Identifiers

CAS 405225-21-0
Molecular Formula C24H24FNO3
Molecular Weight (g/mol) 393.458
InChI Key FDORQEIHOKEJNX-UHFFFAOYSA-N
Synonym nfps, 3h nfps, 3h-nfps, chembl26512, n-3-4'-fluorophenyl-3-4'-phenylphenoxy propyl sarcosine, n-3-1,1-biphenyl-4-yloxy-3-4-fluorophenyl propyl-n-methylglycine, 2-3-1,1'-biphenyl-4-yloxy-3-4-fluorophenyl propyl methyl amino acetic acid, 2-3-4-fluorophenyl-3-4-phenylphenoxy propyl methyl amino acetic acid, d03kvc, d08aym
PubChem CID 5311283
IUPAC Name 2-[[3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid
SMILES CN(CCC(C1=CC=C(C=C1)F)OC2=CC=C(C=C2)C3=CC=CC=C3)CC(=O)O

Specifications

Formula Weight 393.45
Percent Purity >98%
Quantity 10 mg
Chemical Name or Material NFPS

Safety and Handling

Recommended Storage Store at +4°C
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