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NGFR/TNFRSF16/p75NTR Antibody (NGFR5 + NTR/912), Alexa Fluor™ 488, Novus Biologicals™
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Catalog No. NB247967488 Shop All R&D Systems Products
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Catalog No. NB247967488 Supplier Novus Biologicals Supplier No. NBP247967AF488
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Description

Mouse Monoclonal Antibody

NGFR/TNFRSF16/p75NTR Monoclonal specifically detects NGFR/TNFRSF16/p75NTR in Human, Primate, Mouse (Negative), Rat (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen NGFR/TNFRSF16/p75NTR
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone NGFR5 + NTR/912
Conjugate Alexa Fluor 488
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Gene Symbols NGFR
Host Species Mouse
Immunogen NGFR from A875 melanoma cells (NGFR5); Recombinant human p75 NGFR protein (NTR/912)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 4804
Test Specificity It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Target Species Human, Primate, Mouse (Negative), Rat (Negative)
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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