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NGFR/TNFRSF16/p75NTR Antibody (NGFR5), PE/Cy7, Novus Biologicals™
SDP

Catalog No. N247965PEC7 Shop All R&D Systems Products
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N247965PEC7 0.1 mL
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Catalog No. N247965PEC7 Supplier Novus Biologicals Supplier No. NBP247965PECY7
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Description

Mouse Monoclonal Antibody

NGFR/TNFRSF16/p75NTR Monoclonal specifically detects NGFR/TNFRSF16/p75NTR in Human, Feline, Ferret, Monkey, Baboon, Rabbit, Mouse (Negative), Rat (Negative) samples. It is validated for Flow Cytometry.

Specifications

Antigen NGFR/TNFRSF16/p75NTR
Applications Flow Cytometry
Classification Monoclonal
Clone NGFR5
Conjugate PE-Cyanine7
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Gene Symbols NGFR
Host Species Mouse
Immunogen NGFR from A875 melanoma cells
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 4804.0
Test Specificity It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Target Species Human, Feline, Ferret, Monkey, Baboon, Rabbit, Mouse (Negative), Rat (Negative)
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG1 κ
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