Tocris™ NIBR 189

Potent and selective EBI2 (GPR183) receptor antagonist

Manufacturer: Tocris™ 5203/10

 View all options for this product

Catalog No. 52-031-0

  Check Availability
Add to Cart


For Research Use Only


    Product Type NIBR 189
    Inhibitors NIBR 189
    Purity >99
    Molecular Weight 429.31
    Quantity 10mg

    Potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15nM for human and mouse EBI2 receptors respectively). Exhibits selectivity for EBI2 over a panel of other receptors, enzymes and transporters. Blocks oxysterol-induced migration of U937 monocyte cells. Orally bioavailable.

    • Chemical Name: (2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one
    • Formula: C21H21BrN2O3
    • CAS Number: 1599432-08-2
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

Related Products

Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit