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Nicotinamide, 99%, Thermo Scientific Chemicals
Description
Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.
Solubility
Soluble in water, ethanol , glycerol, DMSO , methanol, butanol and chloroform. Slightly soluble in ether.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Specifications
Melting Point | 128°C to 132°C |
Density | 1.4 |
Flash Point | 182°C (360°F) |
Assay Percent Range | 99% |
Quantity | 250 g |
Beilstein | 383619 |
Merck Index | 14,6523 |
Solubility Information | Soluble in water,ethanol ,glycerol,DMSO ,methanol,butanol and chloroform. Slightly soluble in ether. |
Formula Weight | 122.13 |
Percent Purity | 99% |
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Safety and Handling
Hazard Category | H319-H500 |
Hazard Statement | GHS H Statement H319 |
Precautionary Statement | P264b-P280i-P305+P351+P338 |
EINECSNumber | 202-713-4 |
RTECSNumber | QS3675000 |
TSCA | Yes |
Recommended Storage | Ambient temperatures |
RUO – Research Use Only
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