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Nitrotyrosine Antibody (HM.11), Novus Biologicals™
SDP

Catalog No. NB6001024 Shop All R&D Systems Products
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NB6001024 0.05 mg
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Catalog No. NB6001024 Supplier Novus Biologicals Supplier No. NB6001024
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Mouse Monoclonal Antibody

Nitrotyrosine Monoclonal specifically detects Nitrotyrosine in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoassay.

Specifications

Antigen Nitrotyrosine
Applications Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), Immunoassay
Classification Monoclonal
Clone HM.11
Concentration 0.1 mg/mL
Conjugate Unconjugated
Dilution Western Blot 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, Immunoassay
Gene Alias Nitrotyrosine
Host Species Mouse
Immunogen Nitrated KLH
Purification Method Protein G purified
Quantity 0.05 mg
Regulatory Status RUO
Research Discipline Amino Acids Drugs and other small molecules, Lipid and Metabolism, Neuroscience, Neurotransmission, Tyrosine Kinases
Primary or Secondary Primary
Test Specificity This highly specific monoclonal antibody HM.11 reacts with nitrotyrosine, both with the free amino acid as well as with proteins containing nitrotyrosine. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic plaques. Nitrotyrosine is formed in tissues in presence of the active metabolite NO and is a stable end product of nitrosylation of tyrosine. Various pathways including the formation of peroxinitrite lead to nitrotyrosine production.
Target Species Human
Content And Storage Store at 4°C.
Form Purified
Isotype IgG2b
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For Research Use Only

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