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NKX2.2 Antibody (NX2/294), DyLight 488, Novus Biologicals™
SDP

Catalog No. NBP233058G Shop All R&D Systems Products
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NBP233058G 0.1 mL
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Catalog No. NBP233058G Supplier Novus Biologicals Supplier No. NBP233058G
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Description

Mouse Monoclonal Antibody

NKX2.2 Monoclonal specifically detects NKX2.2 in Human, Mouse, Rat, Chicken samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

Antigen NKX2.2
Applications ELISA
Classification Monoclonal
Clone NX2/294
Conjugate DyLight 488
Dilution ELISA
Gene Alias Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B
Gene Symbols NKX2-2
Host Species Mouse
Immunogen Human full-length recombinant NKX2.2 protein (Uniprot: O95096)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4821
Test Specificity Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Target Species Human, Mouse, Rat, Chicken
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG2b κ
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