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NKX2.2 Mouse, Clone: SPM564, Novus Biologicals™
SDP

Catalog No. NBP232884A Shop All R&D Systems Products
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Catalog No. Quantity
NBP232884A 0.1 mg
NBP232884F 0.02 mg
NBP232884B 0.2 mg
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Catalog No. NBP232884A Supplier Novus Biologicals Supplier No. NBP2328840.1MG
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Mouse Monoclonal Antibody

NKX2.2 Monoclonal specifically detects NKX2.2 in Human, Mouse, Rat, Chicken samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen NKX2.2
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone SPM564
Conjugate Unconjugated
Dilution Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. O95096
Gene Alias Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B
Gene Symbols NKX2-2
Host Species Mouse
Immunogen Human NKX2.2 recombinant protein
Purification Method Protein A purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4821
Test Specificity Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Target Species Human, Mouse, Rat, Chicken
Content And Storage Store at 4C.
Form Purified
Isotype IgG2b κ
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