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NLRP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 151821AP

Catalog No. 50-173-0045


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Description

Description

NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1-b-processing activity and is thought to function as a modulator of NF-kappa-B and procaspase-1 activation in macrophages. It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for NALP2.
Specifications

Specifications

NLRP2
0.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9NX02
CLR19.9, NALP2, NBS1, NLRP2, PAN1, PYPAF2
Rabbit
IgG
150 μL
-20°C
Primary
232827, 55655
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
NLRP2
Liquid
NLRP2
NLRP2 Fusion Protein Ag7167
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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