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  5. Tocris Bioscience™ NNC 0640

Tocris Bioscience™ NNC 0640
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Catalog No. p-7199096
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Negative allosteric modulator of glucagon and GLP-1 receptors

NNC 0640 is a negative allosteric modulator of glucagon receptors (pKi = 7.4). Binds to external surface of the transmembrane domain. Also negative allosteric modulator of glucagon-like peptide 1 (GLP-1) receptor. Inhibits GLP-1-mediated cAMP accumulation in vitro.

Specifications

Chemical Name or Material 4-[[(4-Cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2 H-tetrazol-5-ylbenzamide
CAS 307986-98-7
Quantity 10 mg
Target Glucagon-Like Peptide 1 Receptor Modulators
Molecular Formula C29H31N7O4S
Formula Weight 2172
Purity 98%
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