Norfloxacin

Description

A synthetic fluoroquinolone antibiotic | CAS: 70458-96-7 | C16H18FN3O3 | 319.336 g/mol

It finds it application as a fluorinated quinolone antibacterial. It is clinically used to treat urinary tract infections and prostatitis. In neutrophils from cirrhotic subjects, norfloxacin increases expression of IL-10 and heme oxygenase 1 (HO-1) and decreases expression of pro-inflammatory cytokines. Additionally, when complexed with gold(III), norfloxacin binds DNA and inhibits cellular proliferation in several cancer cell lines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in acetic acid. Also soluble in acetone or cloroform. Slightly soluble in water

Notes
Store away from heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Keep it refrigerated.

Specifications

Chemical Identifiers

• CAS: 70458-96-7
• Molecular Formula: C16H18FN3O3
• Molecular Weight (g/mol): 319.336
• MDL Number: MFCD00079532
• InChI Key: OGJPXUAPXNRGGI-UHFFFAOYSA-N
• Synonym: Baccidal; Sebercim
• PubChem CID: 4539
• ChEBI: CHEBI:100246
• IUPAC Name: 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• SMILES: CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O

• Type: Norfloxacin
• Physical Form: Powder
• Melting Point: 220°C to 221°C
• Color: White to Yellow
• Quantity: 1 g
• Merck Index: 14,6700
• Solubility Information: Soluble in acetic acid; Also soluble in acetone or cloroform; Slightly soluble in water
• Formula Weight: 319.33
• Chemical Name or Material: Norfloxacin

Safety and Handling

EINECSNumber	274-614-4
RTECSNumber	VB5005000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only