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NP95/UHRF1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501560480
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50-156-0480 20 μL
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Catalog No. 50-156-0480 Supplier Bethyl Laboratories, Inc Supplier No. A301470AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen NP95/UHRF1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene UHRF1
Gene Accession No. Q96T88
Gene Alias ICBP90, Np95, RNF106, hNP95, E3 ubiquitin-protein ligase UHRF1, RING finger protein 106, huNp95, inverted CCAAT box-binding protein of 90 kDa, nuclear protein 95, nuclear zinc finger protein Np95, transcription factor ICBP90, ubiquitin-like PHD and RING finger domain-containing protein 1, ub
Gene Symbols UHRF1
Host Species Rabbit
Immunogen Between 275 and 325
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29128
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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