Invitrogen™ NPDC1 Monoclonal Antibody (16E4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA112777

Catalog No. 01-674-060

Description

A suggested positive control for this product is brain tissue lysate.

The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptiona levents mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.

Specifications

• Antigen: NPDC1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 3mM sodium azide; pH 7.5
• Gene Accession No.: Q64322, Q9NQX5
• Gene Symbols: NPDC1
• Immunogen: Synthetic peptide corresponding to human NPDC-1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 16E4
• Conjugate: Unconjugated
• Gene: NPDC1
• Gene Alias: AI314472; CAB; CAB-; CAB1; CAB-1; DKFZP586J0523; Neural proliferation differentiation and control protein 1; neural proliferation differentiation control-1 protein; neural proliferation, differentiation and control 1; neural proliferation, differentiation and control gene 1; neural proliferation, differentiation and control, 1; NPDC1; NPDC-1; RP23-47P18.6
• Host Species: Mouse
• Purification Method: Ion-exchange Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18146, 296562, 56654
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid