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  5. Tocris Bioscience™ NPS 2143 hydrochloride

Tocris Bioscience™ NPS 2143 hydrochloride
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Catalog No. 362650R
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Quantity:
10 mg
50 mg
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Catalog No. 36-265-0R

Supplier: Tocris Bioscience™ 3626/50

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Description

Selective calcium-sensing receptor (CaSR) antagonist; orally active calcilytic agent

NPS 2143 hydrochloride is a selective Ca2+-sensing receptor antagonist. Blocks increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells (IC50 = 43 nM). Also stimulates parathyroid hormone secretion from bovine parathyroid cells (EC50 = 41 nM). Orally active calcilytic compound.

Specifications

Quantity 50 mg
Product Type NPS 2143 hydrochloride
Purity >99%
Molecular Weight (g/mol) 445.38
Inhibitors NPS 2143 hydrochloride

For Research Use Only

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