DescriptionThis gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.
|This antibody was raised against a peptide within the C-terminal region of human NRF1.|
|-20°C, Avoid Freeze/Thaw Cycles|
|PBS with 30% glycerol and 0.035% sodium azide; pH 7.5|
|Alpha palindromic-binding protein; Alpha-pal; BOS_4525; C87038; D6Ertd415e; EWG; Nfe2l1_retired; Not really finished protein; nrf; NRF1; NRF-1; nrf1 protein; nrl; Nuclear respiratory factor 1; nuclear respiratory factor-1; SC:BZ3C13.1; SC:bZ3C13.2; transcription factor; ube2h|
|Antigen affinity chromatography|
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